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Test Name: TISSUE TRANSGLUTAMINASE (tTG), IgA
Test Code: 2328215
Alias: LAB723
CPT Code(s): 83516  
Preferred Specimen: 1.0 mL serum
Container: SST (gold)
Alternate Container:

Plain Red (no additive/gel)

Minimum Volume: 0.5 mL serum
This volume may not allow for repeat testing.
Collection Instructions: Allow specimen to completely clot (this can take up to 60 minutes). Centrifuge for 15 minutes as soon as the specimen is clotted. If the specimen is collected in a Plain Red (no additive/gel) tube, transfer the separated serum to a properly labeled plastic transfer tube. Specify specimen type (serum) on transfer tube.
Transport Temperature: Refrigerated
Stability:

Refrigerated: 7 days

Freeze for longer stability

Rejection Criteria:

Hemolysis

Lipemia

Gross bacterial contamination

Limitations:

A serology test alone is not diagnostic for celiac disease.  Results should be used in conjunction with other laboratory test results and the clinical presentation of the patient.

A negative result in an untreated patient does not rule out celiac disease.  This finding can be explained by selective IgA deficiency.  The celiac IgG tests can be used to aid in assessing IgA deficient individuals. 

Schedule: Testing Performed Monday-Friday;  Results in 24-48 hours
Method:

Multiplex Bead Immunoassay

Clinical Significance:

The presence of antibodies can aid in the diagnosis of celiac disease. 

Use:

3/1/22 lw

Updated 07/23/25

Reference Ranges:

< 15 U/ml  = Negative

>=15 U/ml  = Positive

 

The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.

Test Type: