| Test Name: |
CARDIOLIPIN IgG ANTIBODY |
| Test Code: |
2320111 |
| Alias: |
ACA IgG
Antiphospholipids IgG
Immunoglobulin G
LAB3012
|
| CPT Code(s): |
86147
|
| Preferred Specimen: |
1.0 mL serum |
| Container: |
SST (gold) |
| Minimum Volume: |
0.5 mL serum
|
| Transport Temperature: |
Refrigerated |
| Stability: |
Refrigerated: 7 days
|
| Rejection Criteria: |
Hemolysis |
| Limitations: |
Anti-cardiolipin antibodies also occur transiently in a variety of infectious diseases. In these cases, patients positive for anti-cardiolipin antibodies should be retested following an appropriate interval. Confirmed active or seropositive syphilis patients can have elevated cardiolipin antibody levels.
The anti-cardiolipin test can produce false positive results due to cross-reactivity with dsDNA antibodies. |
| Schedule: |
Set-up: Monday and Thursday; Results in 1-5 days |
| Method: |
Multiplex bead immunoassay |
| Clinical Significance: |
Anti-cardiolipin antibodies (ACA) have been strongly associated with venous and arterial thrombosis. These findings were first observed during studies on Systemic Lupus Erythematosus (SLE), a disease whose many symptoms include thrombosis. Of the many autoantibodies found in SLE, two were found to be directed against phospholipids such as cardiolipin. |
| Use: |
Updated: 8/4/25 |
| Reference Ranges: |
Cardiolipin IgG:
Negative <20 GPL
Positive >=20 GPL
|
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The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.
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| Test Type: |
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