| Test Name: |
ANTI-ENA6 PLUS DFS70 AB PROFILE |
| Test Code: |
2194661 |
| Alias: |
520301
LAB15779
|
| CPT Code(s): |
83516
86235 x 6
|
| Test Includes: |
Anti-DFS70; Anti-Sm; Anti-U1 RNP; Anti-Ro (SS-A); Anti-La (SS-B); Anti-Scl-70; Anti-Jo-1 |
| Preferred Specimen: |
3 mL serum |
| Container: |
SST x 2 |
| Alternate Container: |
Red Top x 2 |
| Minimum Volume: |
1.5 mL serum |
| Collection Instructions: |
Allow specimen to completely clot. Centrifuge for 15 minutes when specimen is clotted or within 2 hours of collection. |
| Transport Temperature: |
Refrigerated |
| Stability: |
Room temperature: 7 days
Refrigerated: 14 days Frozen: 60 days |
| Rejection Criteria: |
Grossly hemolyzed; bacterial contamination; lipemic, icteric, non-serum specimen types |
| Limitations: |
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. |
| Additional Information: |
Anti-ENA6 Plus DFS70Ab Profile |
| Schedule: |
Report Available: 14-21 days |
| Performing Lab: |
LabCorp #520301 |
| Clinical Significance: |
Anti-ENA6 Plus DFS70 is designed to facilitate the proper triage of patients with positive Anti-Nuclear Antibodies (ANA) by identifying those most likely to benefit from a rheumatology specialist. It detects the novel Anti-DFS70 along with 6 other clinically useful autoantibodies to ENA, which may help identify systemic lupus erythematous (SLE), mixed connective tissue disease (MCTD), Sjogren's, systemic sclerosis, and idiopathic inflammatory myopathy (IIM). Positive Anti-DFS70 antibodies in isolation may help identify individuals who do not have an AARD (ANA-associated rheumatic disease), especially in the absence of significant clinical findings.
Anti-DFS70 Abs confer a likelihood ratio for the absence of systemic autoimmune rheumatic disease of 10.9 and are detectable in 2% to 22% of healthy individuals and in less than 1% of patients with AARD. |
| Use: |
Updated: 04/29/2025 |
|
The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.
|
| Test Type: |
|