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Test Name:

CREATINE KINASE (CK)/CREATINE KINASE-MB (CK-MB) ISOENZYME

Test Code:

2120296

Alias:

CK/CK-MB
LAB63

CPT Code(s):

82550 82553

Test Includes:

Creatine Kinase

Creatine Kinase-MB Isoenzyme

Preferred Specimen:

2.0 mL plasma

Container:

Lithium Heparin (lt green)

Alternate Container:

Sodium Heparin (green)

SST (gold) - not to be used for in-patients

Minimum Volume:

0.6 mL plasma or serum

Collection Instructions:

Centrifuge for 15 minutes. If the specimen is drawn in an SST tube, allow specimen to completely clot (this can take up to 60 minutes) before centrifuging for 15 minutes. If the specimen is collected in a tube without a gel barrier, centrifuge and transfer the plasma into a properly labeled transfer tube within 2 hours of collection.

Transport Temperature:

Refrigerated

Stability:

Room Temperature: 4 hours

Refrigerated: 48 hours

Limitations:

Evaluation of serum samples may result in up to a -18% bias compared with plasma samples. When serial specimens are being evaluated, the same type of specimen should be used throughout the study.

Schedule:

Set up: Daily; Results in 24-48 hours

Method:

Enzymatic rate (Creatine Kinase)

Two-site immunoenzymatic "sandwich" assay (CK-MB)

Clinical Significance:

Refer to individual tests.

Use:

Updated 2/13/24

Reference Range Table

Result	Units	Gender	Age	Range
CK	IU/L	Female	0 Year - 999 Year	26 - 192
CK	IU/L	Male	0 Year - 999 Year	39 - 308
CK-MB	ng/mL	Both	0 Year - 999 Year	0.6-6.3

The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.

Reference Range Table

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