Test Name: APOLIPOPROTEIN EVALUATION
Test Code: 2196629
Alias: 7018
Apo A1
Apo B
LAB2364
CPT Code(s): 82172(x2)  
Test Includes: Apolipoprotein A1
Apolipoprotein B
Apolipoprotein B/A1 ratio
Preferred Specimen: 1.0 mL serum
Container: SST (gold)
Minimum Volume: 0.5 mL serum
Collection Instructions:
Allow specimen to completely clot (this can take up to 60 minutes). Centrifuge for 15 minutes as soon as the specimen is clotted.
Transport Temperature: Room temperature
Stability:
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 30 days
Rejection Criteria: Grossly lipemic
Schedule: Set up: Mon-Sat; Report available: 2-4 days
Method: Immunoturbidimetric
Performing Lab: Quest Diagnostics Nichols Institute, Chantilly; #7018
Clinical Significance: Apolipoprotein A1 is the primary protein associated with HDL cholesterol. Like HDL cholesterol, increased concentrations are associated with reduced risk of cardiovascular disease. Apolipoprotein B-100 is the primary protein associated with LDL cholesterol and other lipid particles. Like LDL cholesterol, increased concentrations are associated with increased risk of cardiovascular disease. The ratio of these two apolipoproteins correlates with risk of cardiovascular disease.
Use: Updated: 01/23/2026
Reference Ranges:

Apolipoprotein A1
Male:          ≥115 mg/dL
Female:      ≥125 mg/dL
Risk Category          Male                                  Female
Optimal:                         ≥115 mg/dL                  ≥125 mg/dL
High:                              <115 mg/dL                  <125 mg/dL

Apolipoprotein B:  <90 mg/dL
Risk Category
Optimal:                         <90 mg/dL
Moderate:                       90-129 mg/dL
High:                               ≥130 mg/dL

Apolipoprotein B/A1 Ratio
Male:           <0.77
Female:       <0.63
Risk Category          Male                                  Female
Optimal                        <0.77                                 <0.63
Moderate:                     0.77-0.95                          0.63-0.78
High:                             >0.95                                 >0.78

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The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.
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