Test Name: HERPES SIMPLEX VIRUS (HSV) TYPE 1 SPECIFIC ANTIBODY, IgG
Test Code: 2329776
Alias:
HSV-1 IgG Ab
LAB507
CPT Code(s):
86695  
Preferred Specimen:

2.0 mL serum
Container:

SST (gold)
Minimum Volume:

1.0 mL serum
*This volume does not allow for repeat testing.
Collection Instructions:

Allow specimen to completely clot (this can take up to 60 minutes). Centrifuge for 15 minutes. The serum or plasma should be physically separated from contact with cells within 2 hours from the time of collection.

Transport Temperature:

Refrigerated
Stability:

Refrigerated:  7 days
Frozen: 1 month
Rejection Criteria:

Gross hemolysis

Schedule:

Testing performed:  Monday - Friday; Results in 1-3 days
Method:

Multiplex Bead Immunoassay
Performing Lab:
HealthLab   
Clinical Significance:

HSV-1 is generally associated with infection in the tongue, mouth, lips, pharynx and eyes.
As with other serological tests, negative results do not rule out the diagnosis of herpes simplex disease.  The time required to seroconvert following primary infection varies with the individual, the specimen many have been drawn prior the appearance of detectable antibodies.  There are reports of sero-reversion.  When appropriate, e.g., in suspected early herpes simplex disease, the test should be repeated or tested with a different assay.  If on re-testing, the result remains negative, then a second sample should be drawn 4-12 weeks later and testing repeated.  A single positive result only indicates previous immunologic exposure; level of antibody response or class of antibody response may not be used to determine active infection or disease stage. 
Department:
Immunology
Reference Ranges:

< 0.9 is negative, no antibodies detected.

0.9-1.0 is equivocal, obtain an additional sample for testing.

>1.1 is positive, IgG antibody is detected.

Health Lab Test Code Build Information

The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.
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