Test Name: CARDIO IQ® ADVANCED LIPID PANEL AND INFLAMMATION PANEL
Test Code: 2192400
Alias: 94220
Cardio IQ
LAB12301
CPT Code(s): 82172   80061   83695   83704   86141   83698   80061   *83721 (if appropriate)  
Test Includes:

Cardio IQ® Cholesterol, Total
Cardio IQ® HDL Cholesterol
Cardio IQ® Triglycerides
Cardio IQ® Non-HDL and Calculated Components
Cardio IQ® Lipoprotein Fractionation, Ion Mobility
Cardio IQ® Apolipoprotein B
Cardio IQ® Lipoprotein (a)
Cardio IQ® hs-CRP
Cardio IQ® Lp-PLA2 Activity

If Triglyceride is >400 mg/dL, then Cardio IQ® Direct LDL will be performed at an additional charge (CPT code(s): 83721).
Preferred Specimen: 6.0 mL serum
Container:

3-SST (gold)

**Do not combine samples for this test with other tests. Draw separate samples for this test.
Minimum Volume: 3.0 mL serum (2-SST)
Collection Instructions:

Allow specimen to completely clot (this can take up to 60 minutes). Centrifuge for 15 minutes.

Transport Temperature: Refrigerated
Stability: Room temperature: unacceptable
Refrigerated: 7 days
Frozen: 15 days
Rejection Criteria:

Gross hemolysis

Gross lipemia

Moderately and grossly icteric

Samples stored and shipped room temperature
Limitations: The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.
Additional Information: The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for...Cholesterol, Uric Acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hr, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.
Schedule: Set up: Daily; Report available 3-7 days 
Method:

Enzymatic

Immunoassay (IA)

Immunoturbidimetric

Ion Mobility

Spectrophotometry (SP)
Performing Lab: Quest Diagnostics, Wood Dale > CHL #94220
Clinical Significance: The 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults recommend matching the intensity of statin treatment with the absolute risk of cardiovascular events. However, the standard lipid panel alone does not provide a complete assessment of absolute risk of CVD. Adding advanced CVD markers (ion mobility, apob, lp(a), hs crp and lppla2) in addition to the lipid panel will improve assessment of the CVD risk.
Use:

Updated: 11/18/2025

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